Project Zeros
Founder Tales

EP 113 · Founder Tales · 53 min · PT

Transformou uma doença rara numa startup

Aug 3, 2026

About this conversation

Andrea's diagnosis of Müllerian agenesis—born without a uterus and upper vagina—came only after years of diagnostic chaos. The discovery happened during surgery, after multiple misdiagnoses and invasive procedures that doctors attributed to psychological causes. That bureaucratic failure planted a seed. Working later as a nurse, she noticed the same fragmented, sluggish diagnostic patterns repeating across fertility cases, where conditions like polycystic ovary syndrome take nine years to diagnose despite clear medical criteria. The system wasn't broken randomly; it was structurally fractured.

Enhanced Fertility launched in 2021 as a marketplace for at-home hormone and sperm testing, designed to accelerate the diagnostic funnel. But after expanding to Europe in 2023, Andrea discovered that innovation adoption wasn't a regulatory problem—it was cultural. European healthcare professionals trusted established protocols over faster alternatives, even when those alternatives worked. So the company pivoted into something more ambitious: an operating system for fertility clinics powered by agentic AI.

The platform now maps the entire patient journey into 74 discrete steps across six phases, embedding clinical guidelines, cost structures, and decision-making protocols into autonomous agents. One agent handles initial website inquiry. Another manages patient coordination—scheduling tests that must align with menstrual cycles. Others handle insurance verification, clinical decision support, and post-treatment follow-up. Each clinic configures its own workflow, but the underlying model is the same: remove friction, enforce evidence-based timing, and scale without hiring.

What makes this different from basic CRM is depth. The system isn't just tracking data; it's encoding fertility medicine itself. That specialization—what Andrea calls "deep vertical specialization"—is why the technology can make real decisions, not just route information. A 35-year-old woman's declining egg quantity and quality demands different timing than a 28-year-old's investigation for endometriosis. The system knows this. Most healthcare software doesn't.

The company is nine people. Andrea and her co-founder husband Frank have deliberately split responsibilities: she owns clinical decisions, he owns technology. Teams are divided the same way. The arrangement works because both are founders—neither can pretend the work ends at 6 PM—but it requires explicit task boundaries to function. They spent one evening watching television; Frank was still on his laptop solving technical problems. That's the cost of aligned ambition.

Thirty-eight babies have been born from patients who entered the funnel through Enhanced Fertility's protocols. The company rings a bell in its Lisbon office each time. It's a metric that separates this from ordinary SaaS: success isn't a conversion, it's a human.